The TIME100 Most Influential People of 2025 honors African changemakers and individuals who are driving change and shaping the future across various sectors across the globe.
From political leaders who are redefining governance to cultural icons and trailblazing scientists, these individuals represent the diverse forces driving Africa’s development and global impact.
Their recognition showcases Africa’s increasing role in global discussions on health, technology, leadership, and cultural exchange.
These figures are not just influential in their home countries but are setting trends and inspiring change worldwide.
Speaking on the 2025 TIME100 list, Chief Executive Officer Jessica Sibley said, “The list recognizes the leaders shaping the world today and defining its future.”
TIME Editor in Chief Sam Jacobs added in his letter to readers that “the 2025 list includes six members of the Trump Administration, 16 corporate CEOs—a record—and a sign of the emergence of business leaders filling a leadership void, alongside nine leaders fighting for justice, equality, and democracy, at a moment when the rights of so many are at stake. Members of the list come from 32 countries.”
Donald Trump makes his seventh appearance on the list, the most of any individual this year. Other repeat honorees include Elon Musk (6), Mark Zuckerberg (5), Serena Williams (3), Lorne Michaels (3), Simone Biles (3), Kristen Wiig (2), Ed Sheeran (2), Tedros Adhanom Ghebreyesus (2), Demis Hassabis (2), Scarlett Johansson (2), Megyn Kelly (2), Blake Lively (2), Javier Milei (2), Miuccia Prada (2), Joe Rogan (2), and Ted Sarandos (2).
The 9 most influential Africans
These individuals exemplify the diverse talents and contributions of Africans on the global stage, each making significant strides in their respective fields.
1. Dr. Tedros Adhanom Ghebreyesus – Director-General of the World Health Organization (WHO)
As the first African to lead the WHO, Dr. Tedros (Ethiopia) has been instrumental in global health initiatives, particularly in response to the COVID-19 pandemic. His leadership has been pivotal in steering international health policies and ensuring equitable access to vaccines and medical resources.
2. Dr. Duma Boko – President of Botswana
Dr. Boko’s tenure as Botswana’s president has been marked by progressive reforms aimed at enhancing democratic governance and economic diversification. His policies focus on sustainable development, education, and technological innovation, positioning Botswana as a model for good governance in Africa.
3. Mo Abudu – Nigerian Media Mogul
Often referred to as the “Oprah of Africa,” Mo Abudu has revolutionized African media through her company, EbonyLife Media. She has played a crucial role in showcasing African stories on global platforms, including Netflix and international film festivals, thereby elevating African narratives in global media.
4. Dr. Christian Happi – Nigerian Scientist and Genomics Pioneer
Dr. Happi is renowned for his groundbreaking work in genomics and infectious diseases. His research has been instrumental in developing diagnostic tools and treatments for diseases prevalent in Africa, contributing significantly to the continent’s healthcare advancements.
5. Dr. Ismahane Elouafi – Moroccan Agricultural Biotechnologist
As a leading figure in agricultural biotechnology, Dr. Elouafi’s work focuses on enhancing food security through sustainable agricultural practices. Her research aims to develop drought-resistant crops, which are vital for combating food insecurity in arid regions of Africa.
6. Kwame Onwuachi – Nigerian-American Chef and Culinary Innovator
Chef Onwuachi has gained acclaim for his innovative approach to African and Caribbean cuisine. His culinary creations blend traditional flavors with contemporary techniques, offering a unique dining experience that celebrates African heritage.
7. Mickalene Thomas – African-American Artist
While American by nationality, Mickalene Thomas’ work is deeply influenced by African culture. Her vibrant and textured portraits celebrate African-American womanhood and identity, drawing inspiration from African art traditions and aesthetics.
8. Fatou Baldeh – Gambian women’s rights activist
Fatou Baldeh, has been honored as one of TIME’s Women of the Year 2025. She is recognized for her unwavering commitment to ending female genital mutilation (FGM) in The Gambia.
9. Angeline Murimirwa – CEO, CAMFED
Angeline (Zimbabwe), an Africa Education Medal 2024 finalist, is the CEO of CAMFED, helping millions of girls go to school in Ghana, Malawi, Tanzania, Zambia, and Zimbabwe. Just like her, these young women may also be tomorrow’s leaders.
